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Moumoujus

DIPEPTIDE-13.

Insufficient Data CAS - / SKIN CONDITIONING

Dipeptide-13, a synthetic peptide comprising L-Glutamic acid and L-Tryptophan, represents a foundational compound for immunomodulatory and regenerative applications. Although direct clinical data for Dipeptide-13 are limited, its lipo-derivative, Myristoyl Dipeptide-13, has demonstrated significant cellular benefits for skin and hair.

Summary

Immunomodulatory Agent Anti-stress Agent Anti-tumor Agent Cell Proliferation Enhancer Melanin Synthesis Stimulator Wound Healing Agent Anti-aging Agent Hair Growth Stimulator

Science

Mechanism of Action

Dipeptide-13, also identified as Thymogen, primarily operates through immunomodulatory and anti-stress pathways. Its lipo-derivative, Myristoyl Dipeptide-13, extends this mechanism by actively promoting the proliferation of critical dermal cells, including dermal papilla cells, fibroblasts, and keratinocytes. Furthermore, it stimulates melanin synthesis within melanocytes and accelerates the processes of wound healing and re-epithelialization.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding 'dusting' behavior or common misuse in minimal concentrations was found for Dipeptide-13, suggesting it is not typically 'dusted' in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a peptide containing tryptophan, Dipeptide-13 is susceptible to degradation through oxidation, hydrolysis, and microbial contamination, particularly when dissolved in water. While general dipeptides maintain stability across a pH range of 5.0 to 7.4, the precise optimal pH for Dipeptide-13's stability remains unspecified. Incorporating stabilizers like trehalose can contribute to enhanced peptide integrity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Dipeptide-13 has not undergone a dedicated Cosmetic Ingredient Review (CIR) safety assessment. General CIR perspectives on peptides suggest they are typically safe when formulated to be nonirritating and are not employed in conditions where N-nitroso compounds might form. Specific data regarding its irritation or sensitization potential for Dipeptide-13 itself is currently unavailable.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While its lipo-derivative, Myristoyl Dipeptide-13, exhibits substantial promise in cellular regeneration, anti-inflammatory effects, and hair health, direct and independent clinical data for Dipeptide-13 itself are largely insufficient to establish a precise efficacy profile.

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