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DIMETHYLOLPROPIONIC ACID.

Valuable CAS 4767-03-7 / NOT REPORTED

Dimethylolpropionic Acid (DMPA) is a trifunctional organic acid utilized as a key intermediate in cosmetic and personal care formulations. It enhances product texture, spreadability, and moisture retention by contributing to the structural integrity of formulations.

Summary

Intermediate for polymeric thickeners Intermediate for film-formers Intermediate for emulsion stabilizers Texture enhancer Spreadability enhancer Moisture retention contributor

Science

Mechanism of Action

DMPA functions by integrating into polymer backbones, where its tertiary carboxylic group can be neutralized with a base. This neutralization promotes the water dispersibility and solubility of the resulting resins, making DMPA instrumental in developing polymeric thickeners, film-formers, and emulsion stabilizers. Its hydrophilic properties also contribute to improved product texture and spreadability.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Commonly dusted

Dimethylolpropionic Acid is a free-flowing white crystalline solid, posing a risk of dust exposure during handling. Airborne dust can cause mechanical irritation to the skin, eyes, and respiratory tract, and also presents a risk of dust explosion.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

DMPA is an odorless, white crystalline solid, stable under normal conditions but hygroscopic. Its pKa is 4.16 ± 0.15, and a 50 g/L aqueous solution at 20°C has a pH of 2.6. Its acidic group facilitates water solubility or dispersibility of resins post-neutralization with a base. It is soluble in water (10.1-11 g/100g at 25°C) and polar organic solvents.

Conflicts

  • Oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Dimethylolpropionic Acid exhibits low systemic toxicity, with an oral LD50 > 5000 mg/kg in white mice. It is not irritating to intact skin but may cause slight irritation to abraded skin and moderate irritation to eyes (conjunctival area). Prolonged or repeated skin contact may lead to dryness or mild irritation. GHS classifications indicate serious eye irritation (H319) and potential respiratory irritation (H335). Its specific cosmetic safety status has not been evaluated by CIR, SCCS, or FDA, though FDA records show its use in food contact substances.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Dimethylolpropionic Acid is a valuable formulation ingredient, crucial for enhancing the structural integrity and sensory characteristics of cosmetic products through its role in creating effective thickeners, film-formers, and emulsion stabilizers.

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