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DIMETHYL SULPHIDE.

Questionable CAS 75-18-3 / PERFUMING

Dimethyl Sulphide functions primarily as a potent fragrance component, contributing to specific sensory profiles such as gourmand, fruity, rose, or sea-breeze accords, typically utilized at extremely low dilutions in perfumery. It does not offer direct therapeutic benefits to the skin.

perfuming agent fragrance ingredient

Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH ≤7.9
0 7 14

Stability

Dimethyl Sulphide is stable when stored under recommended conditions. However, its concentrations notably decrease when the pH rises above 8.0, with a rapid degradation rate observed in alkaline solutions. It is also a highly flammable liquid, and its vapors can form explosive mixtures with air.

Conflicts

  • acids
  • diazo compounds
  • azo compounds
  • halocarbons
  • isocyanates
  • aldehydes
  • alkali metals
  • nitrides
  • hydrides
  • strong reducing agents
  • dibenzoyl peroxide (explosive decomposition)
  • xenon difluoride (explosive decomposition)
  • oxygen (explosive interaction at 210 °C and above)

Safety

CIR Status
Not reviewed
Sensitization risk Low

A RIFM safety assessment indicates that Dimethyl Sulphide does not pose a safety concern for skin sensitization at current, declared usage levels. A human maximization test demonstrated no skin sensitization reactions at a concentration of 1% or an application of 690 µg/cm². It is not expected to induce phototoxicity or photoallergenicity. However, it is classified as an eye and skin irritant; repeated contact with the skin may disrupt its natural lipid barrier, potentially leading to irritation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Due to its primary function as a fragrance agent lacking direct skin benefits and its documented irritant potential despite a low sensitization risk, the inclusion of Dimethyl Sulphide in precision skincare formulations is questionable.


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