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DIMETHYL MALEATE.

Avoid CAS 624-48-6 / 23055-10-9 / SKIN CONDITIONING - EMOLLIENT, SOLVENT

Dimethyl Maleate functions primarily as an emollient and solvent within cosmetic formulations. However, comprehensive research highlights significant safety concerns, classifying it as highly corrosive, a severe irritant, and a potent skin sensitizer.

Emollient Solvent Skin Conditioning Agent

Science

This ingredient operates as an emollient, contributing to skin softening and smoothing by potentially establishing a protective barrier that minimizes moisture evaporation. Additionally, it serves as a solvent, facilitating the integration and dissolution of other components within a cosmetic formulation.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

While not typically 'dusted' for marketing claims, the absence of proven cosmetic benefits at safe concentrations, combined with severe safety concerns, renders its inclusion in skincare highly problematic rather than merely ineffective.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk High

Dimethyl Maleate has not undergone specific review by the Cosmetic Ingredient Review (CIR) Expert Panel for cosmetic safety. It is classified as highly corrosive to both skin and eyes, causes significant skin irritation, and is identified as a potential skin sensitizer. Human patch test studies have demonstrated sensitization reactions at concentrations as low as 0.1%. GHS classifications include warnings for severe skin burns, serious eye irritation, and allergic skin reactions. While the FDA approves it as a food contact substance for industrial use as a stabilizer in PVC polymerization at up to 0.1%, this pertains to industrial application and not cosmetic safety for direct skin contact.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given its classification as highly corrosive, a severe irritant, and a potent skin sensitizer, Dimethyl Maleate presents unacceptable risks and should be entirely avoided in skincare formulations.


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