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Moumoujus

DIMETHYL-4-ISOHEPTENAL DIMETHYL ACETAL.

Questionable CAS 67674-46-8 / PERFUMING

DIMETHYL-4-ISOHEPTENAL DIMETHYL ACETAL, often referred to as grapefruit acetal, is a cosmetic ingredient valued primarily for its perfuming properties. While some assessments indicate low general safety concerns, its GHS classification warns of potential skin and eye irritation. Its optimal formulation stability exists in neutral to mildly alkaline conditions.

Summary

Fragrance

Science

Mechanism of Action

This compound primarily functions by imparting a pleasant aromatic profile to cosmetic products. There is no evidence to suggest it possesses direct biological mechanisms of action or provides specific therapeutic benefits to the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding 'dusting' or misrepresentation of this ingredient's efficacy was found in the provided research.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Acetals are inherently susceptible to hydrolysis, particularly under acidic conditions, which can lead to the formation of their corresponding aldehydes. This ingredient demonstrates good stability in neutral to mildly alkaline matrices, including body lotions, shampoos, soaps, and powders. However, it exhibits poor stability in strongly acidic or alkaline environments (e.g., citric acid cleaners, bleach) and in strongly oxidative conditions, such as those found in AP roll-on products.

Conflicts

  • strong acids
  • strong bases
  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not reviewed this ingredient. While EWG Skin Deep rates it with 'LOW' concerns across several toxicity categories, and Environment Canada classifies it as not expected to be toxic or harmful, GHS classification for 'grapefruit acetal' indicates it 'Causes skin irritation (Category 2)' and 'Causes serious eye irritation (Category 2A)'. These classifications suggest a moderate risk of direct irritation upon contact. Recommended usage levels in fragrance concentrate are noted to be up to 10%.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

As a primary fragrance agent with no known direct skin benefits and a documented moderate risk of skin irritation via GHS classification, DIMETHYL-4-ISOHEPTENAL DIMETHYL ACETAL's inclusion is questionable for a precision skincare formulation focused on targeted epidermal efficacy and minimal irritation.

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