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Moumoujus

DIMETHYL 2,6-NAPHTHALATE.

Insufficient Data CAS 840-65-3 / SKIN CONDITIONING

Dimethyl 2,6-naphthalate is a synthetic organic compound primarily employed in industrial applications, notably as a monomer for high-performance polymers like polyethylene naphthalate (PEN). While it holds FDA recognition for use in certain food contact substances, its specific utility and safety profile within topical skincare formulations are largely unexplored.

Summary

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient exhibits stability under typical recommended storage conditions. It possesses a reported melting point between 187-193 °C, indicating high thermal stability.

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has identified 'insufficient data' for a comprehensive safety assessment of Dimethyl 2,6-naphthalate. While it is listed by the FDA as an indirect additive for food contact substances, an OECD SIDS report (2000) indicated low acute oral toxicity in rats, with an LD50 greater than 2,000 mg/kg. The report also established a No Observed Adverse Effect Level (NOAEL) of 1000 mg/kg/day in rats for repeated dose and reproductive toxicity, confirming it is not genotoxic. However, critical data regarding skin irritation and sensitization were not available in the SIDS report, leaving a significant gap in its dermatological safety profile.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Due to a complete lack of specific research on its mechanism of action, clinical efficacy, and skin-specific safety (irritation, sensitization, comedogenicity), the suitability of Dimethyl 2,6-naphthalate for skincare remains entirely unknown, warranting an 'insufficient-data' classification.

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