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DILAURYL THIODIPROPIONATE.

Valuable CAS 123-28-4 / ANTIOXIDANT

Dilauryl Thiodipropionate is a multifaceted ingredient primarily valued as a non-phenolic antioxidant and sequestering agent, crucial for maintaining product integrity and stability. On the skin, it also offers emollient benefits, promoting moisturization and reinforcing the skin's protective barrier, with some historical research indicating a potential role in improving the appearance of discolorations.

Summary

antioxidant sequestering agent emollient

Science

Mechanism of Action

Dilauryl Thiodipropionate contributes to skin health through several mechanisms. It acts as an antioxidant by inactivating hydroperoxides and scavenging free radicals, thereby protecting the skin from oxidative stress and environmental damage. Furthermore, its emollient properties enhance skin texture, deliver essential moisturization, and support the formation of a robust skin barrier, which helps to reduce transepidermal water loss. Within formulations, it also functions as a sequestering agent, preventing unwanted reactions between ingredients and ensuring product stability.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Older research suggests it may play a role in fading the appearance of discolorations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 6 – 7
0 7 14

Stability

Dilauryl Thiodipropionate exhibits chemical stability under standard ambient conditions and can tolerate heat. Its stability is optimal at neutral or slightly acidic pH, with a half-life estimated at 2.8 years at pH 7, compared to 104 days at pH 8. For proper incorporation, it requires pre-dissolving in fragrance, emollients, or nonionic surfactants.

Synergies

  • primary phenolic antioxidants

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel deems Dilauryl Thiodipropionate safe for use in cosmetic and personal care products, provided it is formulated to be non-irritating. Typical usage concentrations are 1% or less, with 0.05% reported as non-irritating and non-sensitizing in human volunteer tests. While some formulations at concentrations up to 4% have caused irritation in certain subjects, others did not. The FDA recognizes it as Generally Recognized As Safe (GRAS) for use as a chemical preservative in foods, limited to 0.02% of the fat or oil content, and for use in food packaging materials.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Dilauryl Thiodipropionate is a valuable ingredient for both product stability and skin conditioning, offering antioxidant protection and emollient benefits, with a favorable safety profile at recommended concentrations.

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