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DIISOPROPYL NONYL PHOSPHINE OXIDE.

Insufficient Data CAS 1507344-37-7 / SKIN CONDITIONING

DIISOPROPYL NONYL PHOSPHINE OXIDE is a Di-isopropyl-phosphinoyl-alkane (DIPA compound) designed to induce a physiological cooling sensation by stimulating sensory neurons in the skin. Its unique 'reservoir effect' mechanism suggests prolonged action, potentially offering sustained relief from various sensory discomforts and contributing to a refreshed skin appearance.

Sensory agent Cooling agent Anti-fatigue agent Refreshing agent

Science

As a Di-isopropyl-phosphinoyl-alkane (DIPA compound), DIISOPROPYL NONYL PHOSPHINE OXIDE functions topically by stimulating both dynamic and static sensory neurons, thereby eliciting a physiological cooling sensation. The sustained duration of this sensory effect is believed to stem from the availability of its phosphorus oxide for hydrogen bonding, combined with a 'reservoir effect' within the skin, which allows for the reactivation of residual compound to continue neuronal stimulation.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This DIPA compound is noted for its ease of formulation. Specific optimal pH ranges for stability have not been identified for this exact ingredient.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Currently, there are no dedicated safety assessments for DIISOPROPYL NONYL PHOSPHINE OXIDE by major cosmetic regulatory bodies such as the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS). While other phosphine oxides have been evaluated in distinct contexts, such as Trimethylbenzoyl Diphenylphosphine Oxide in nail products or as a component of certain pharmaceutical drugs, these findings do not directly translate to the safety profile of this specific ingredient for cosmetic skin applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

DIISOPROPYL NONYL PHOSPHINE OXIDE offers a unique mechanism for a physiological cooling sensation with a potential reservoir effect, but comprehensive safety and clinical efficacy data for cosmetic application are currently limited.


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