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Moumoujus

DIISOPROPYL BENZALDEHYDE.

Insufficient Data CAS 68459-95-0 / PERFUMING

Diisopropyl Benzaldehyde is an aromatic compound primarily utilized for its perfuming characteristics in cosmetic formulations. While direct skincare-specific studies are currently unavailable, insights from structurally related compounds suggest potential anti-inflammatory properties, awaiting dedicated validation for this specific ingredient.

Summary

perfuming

Science

Mechanism of Action

While direct mechanistic studies for Diisopropyl Benzaldehyde in skin are lacking, research on related Benzaldehyde derivatives indicates potential anti-inflammatory pathways. In *in vitro* settings, these derivatives have demonstrated the ability to inhibit the release of nitric oxide (NO) and reactive oxygen species (ROS). They also suppressed the protein expression of key inflammatory markers such as IL-6, iNOS, and COX-2. Further anti-inflammatory actions include inactivating the NF-κB pathway and inducing heme oxygenase-1 (HO-1) expression through Nrf2 translocation, suggesting a broad scope of potential anti-inflammatory effects that may extend to Diisopropyl Benzaldehyde.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Specific stability data for Diisopropyl Benzaldehyde is not available. However, its parent compound, Benzaldehyde, is known to be stable under recommended conditions but can oxidize in air to benzoic acid and is sensitive to light. These considerations may be relevant for Diisopropyl Benzaldehyde.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Diisopropyl Benzaldehyde (specifically 2,4-diisopropyl benzaldehyde, CAS 68459-95-0) currently has no GHS classification, hazard statements, or precautionary statements identified. The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed this compound. However, the parent compound, Benzaldehyde (CAS 100-52-7), was concluded to be safe for cosmetic use, with maximum reported concentrations of 0.2% in non-spray face and neck products and 0.5% in perfumes. Benzaldehyde is also classified as a Generally Regarded As Safe (GRAS) food additive in the United States.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

With a primary role as a perfuming agent and a lack of direct studies on its skin efficacy and safety, Diisopropyl Benzaldehyde's value in precision skincare extends only to fragrance, necessitating further research for any other purported benefits.

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