Science
Mechanism of Action
As a plasticizer, Diisononyl Phthalate contributes to the suppleness and structural integrity of various materials. In skincare, its mechanism involves modifying a product's rheology to enhance its feel and application. It also acts as a solvent and solubilizer, potentially facilitating the improved delivery and absorption of other cosmetic components on the skin.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Diisononyl Phthalate reacts exothermically with strong acids, generating isononyl alcohol and phthalic acid. Similar heat is produced upon interaction with caustic solutions (strong bases), indicating potential instability in extreme pH environments.
Conflicts
- strong acids
- caustic solutions (strong bases)
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not explicitly reviewed Diisononyl Phthalate (DINP), though other phthalates (DBP, DMP, DEP) were deemed safe for cosmetic use. The Scientific Committee on Consumer Safety (SCCS) identified DINP at 26 mg/kg in one perfume sample and noted toxicological effects in rats following oral administration, including increased liver and kidney weights, with a No Observed Adverse Effect Level (NOAEL) of 15 mg/kg body weight/day. While the FDA states it lacks evidence of safety risk from phthalates generally used in cosmetics, Congress has banned DINP in children's toys and childcare articles exceeding 0.1%. The Australian Industrial Chemicals Introduction Scheme (AICIS) reported minimal skin and eye irritation, and a low likelihood of skin sensitization. However, Diisononyl Phthalate is listed under California Prop 65 as a chemical known to cause cancer.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its classification under California Prop 65 as a known carcinogen and evidence of systemic toxicity in animal studies from the SCCS, Diisononyl Phthalate is not recommended for inclusion in Moumoujus formulations, despite minimal topical irritation concerns.
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References
Sources