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DIHYDROXYPROPYL DIDEHYDROLATANOPROSTAMIDE.

Avoid / HAIR CONDITIONING

Dihydroxypropyl Didehydrolatanoprostamide is a synthetic prostaglandin analogue primarily utilized for its ability to stimulate hair follicles, leading to enhanced eyelash and eyebrow growth. However, its inclusion in cosmetic formulations is a subject of significant regulatory concern due to its potent pharmacological activity and unaddressed safety profile.

Eyelash growth promotion Hair follicle stimulation

Science

This ingredient functions as a prostaglandin analogue, a class of compounds recognized for influencing hair follicle activity. Its mechanism involves direct stimulation of hair follicles, promoting their growth cycle, which has been observed clinically as a side effect when this class of substances is used in medical treatments like glaucoma.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Insufficient data
Pregnancy
Caution
Sensitization risk Unknown

Dihydroxypropyl Didehydrolatanoprostamide has been identified by the SCCS as a prostaglandin analogue possessing potent pharmacological effects. Both the SCCS and CIR have concluded there is insufficient data to support its safety for use in cosmetic products, particularly for promoting eyelash and eyebrow growth. Concerns stem from its strong biological activity even at minimal concentrations, and crucially, a lack of data to definitively exclude potential adverse reproductive and developmental toxicities. Regulatory bodies globally have raised general alarms regarding the use of prostaglandin analogues in cosmetics.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Avoid

Despite its known ability to stimulate hair growth, Dihydroxypropyl Didehydrolatanoprostamide is strongly advised against in cosmetic formulations due to significant safety concerns, including a lack of data regarding reproductive and developmental toxicity.


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References