Science
Mechanism of Action
This ingredient operates by modulating hair follicle activity, a characteristic shared with other prostaglandin F2α analogs. Its mechanism extends to influencing aqueous humor dynamics, primarily by increasing uveoscleral outflow, and regulating matrix metalloproteinases. This enzymatic activity facilitates the remodeling of the extracellular matrix, which can alter tissue permeability and consequently impact pathways associated with hair growth.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) has expressed considerable general concern regarding the use of prostaglandin analogs in cosmetic products, particularly those intended for application near the eye. This concern stems from their potent pharmacological activity and potential to elicit effects even at very low concentrations. While Dihydroxypropyl Dehydrolatanoprostamide is classified within this analog group, a specific safety opinion or CIR assessment on this individual compound is currently unavailable. Known side effects associated with prostaglandin analogs include periocular skin discoloration and deepening of the upper eyelid sulcus.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its established mechanism for hair growth, the significant general safety concerns from regulatory bodies regarding prostaglandin analogs, combined with the absence of a specific safety assessment for Dihydroxypropyl Dehydrolatanoprostamide, makes its inclusion questionable in precision skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources