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Ingredient directory

Dihydroquercetin Glucoside

Dihydroquercetin glucoside is a potent antioxidant, a glycosylated form of dihydroquercetin, engineered for improved solubility and stability. It provides multi-functional benefits, including anti-aging, skin brightening, and anti-inflammatory effects.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antioxidant Skin conditioning Anti-inflammatory Skin whitening Collagen booster Antibacterial Oil regulation

Science

It acts as a strong antioxidant, inhibiting oxidative stress and protecting collagen and elastin fibers by reducing MMP activity. It also promotes collagen synthesis, exhibits anti-inflammatory properties, and non-competitively inhibits tyrosinase for skin whitening.


Research

Medium confidence
Effective range 0.1–1%
Optimal

N/A

Key findings

  1. 01 Demonstrated efficacy in reducing melanin production in a whitening product (0.1-1%).
  2. 02 Showed potential for treating atopic dermatitis in mice by decreasing inflammatory markers.

Transparency

Not commonly dusted

There is no information to suggest this ingredient is commonly 'dusted' or used at ineffective concentrations in formulations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While its precursor is unstable, glycosylation significantly enhances dihydroquercetin glucoside's solubility and stability. It is oxygen-sensitive, requiring protection in formulations.

Synergies

  • Alpha-tocopherol (Vitamin E)

Conflicts

  • Oxygen

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Its precursor, dihydroquercetin, is INCI registered as an antioxidant and generally recognized as safe (GRAS) by the FDA for certain food uses. While the specific glucoside hasn't been individually reviewed by CIR, related saccharides are generally considered safe.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Dihydroquercetin glucoside is a promising multi-functional ingredient offering significant antioxidant, anti-inflammatory, and brightening benefits across various skin types.


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