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DIHEXYL SODIUM SULFOSUCCINATE.

Valuable CAS 6001-97-4 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTANT - HYDROTROPE

Dihexyl Sodium Sulfosuccinate is an anionic surfactant primarily functioning as an emulsifier, wetting agent, and hydrotrope. It enhances formulation stability and improves ingredient solubility, contributing to homogeneous and easily applicable skincare products.

Anionic Surfactant Emulsifier Wetting Agent Dispersing Agent Hydrotrope Soothing

Science

As an anionic surfactant, it lowers surface tension to blend immiscible liquids, form micelles, and boost foam quality. It also acts as a hydrotrope, increasing the solubility of poorly soluble active ingredients within formulations.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a repeated insult patch test, data extrapolated from Dioctyl Sodium Sulfosuccinate showed no sensitization in 110 individuals, though erythema was noted at concentrations ≤5%.
  2. 02 Extrapolated data indicated little to no ocular irritation at 10%.
  3. 03 Extrapolated data demonstrated severe ocular irritation at 25%.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Highly water-soluble (364 g/L), it forms clear solutions and is stable within an optimal pH range of 5.0 to 7.0. It promotes micelle formation and supports overall formulation stability.


Safety

CIR Status
Safe as used
Max tested
4.4%
Sensitization risk Low

The CIR Expert Panel deemed it safe as used in cosmetics, up to 4.4%, when formulated to be non-irritating. This assessment is based on extrapolated data; formulations require careful consideration due to its classification as a cumulative irritant.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Valuable

A versatile anionic surfactant and hydrotrope, Dihexyl Sodium Sulfosuccinate is valuable for creating stable, homogeneous formulations, though careful concentration management is necessary to mitigate potential irritancy.


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