Science
Mechanism of Action
Rich in carotenoids (e.g., astaxanthin), essential amino acids, and tannins, this extract offers antioxidant defense. Its polysaccharides reduce inflammation by decreasing pro-inflammatory cytokines IL1-β and TNF-α.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In vitro studies showed Digenea Simplex chloroform extract nanosuspension (ChlE-NS) exhibited antioxidant activity with IC50 values of 36.86% (DPPH) and 63.5% (ABTS).
- 02 An animal study (60 mg/kg in mice) demonstrated anti-inflammatory and antinociceptive activities, reducing edema and decreasing IL1-β and TNF-α levels.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Nanosuspension techniques can enhance aqueous solubility and bioactivity. FTIR analysis showed no incompatibility with polyvinyl alcohol (PVA) when formulated as a nanosuspension.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has insufficient data to assess its safety for cosmetic formulations. No specific FDA status or maximum concentration has been reported.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While exhibiting promising antioxidant and anti-inflammatory properties in preliminary studies, further human safety and efficacy data are required for a comprehensive assessment.
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