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Moumoujus

DIETHYLENETRIAMINE PENTAMETHYLENE PHOSPHONIC ACID.

Valuable CAS 15827-60-8 / CHELATING

A potent chelating agent, Diethylenetriamine Pentamethylene Phosphonic Acid (DTPMPA) stabilizes cosmetic formulations by binding to metal ions. It prevents discoloration and degradation, ensuring product integrity and active ingredient efficacy.

Summary

Chelating Agent Antioxidant Stabilizer

Science

Mechanism of Action

DTPMPA forms stable water-soluble complexes with multivalent metal ions such as calcium and iron, preventing their precipitation. This action safeguards formulations from unwanted reactions, product discoloration, and acts as an effective peroxide stabilizer.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

DTPMPA exhibits excellent hydrolytic and thermal stability over a broad pH range, with multiple ionization states (pKa 2.8-12.04). It is normally supplied as a water-soluble salt to prevent crystallization in concentrated solutions.

Conflicts

  • Bases
  • Amines
  • Metals (corrosive with moisture)
  • Reducing agents
  • Oxidizing materials
  • Alkalis (violent reaction)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the concentrated acid form is classified as corrosive, the salt form is a mild skin irritant. In cosmetics, DTPMPA is typically used in low, diluted concentrations as a chelator, where irritancy is expected to be low.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

DTPMPA is a valuable formulation ingredient, ensuring product stability and protecting active ingredients by effectively chelating metal ions across various pH and temperature conditions.

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