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DIETHYL OXALATE.

Avoid CAS 95-92-1 / CHELATING, FRAGRANCE, HAIR CONDITIONING, PLASTICISER, SOLVENT

Diethyl Oxalate functions as a versatile ingredient, primarily serving as a solvent, plasticizer, chelating agent, and fragrance in cosmetic formulations.

chelating fragrance hair conditioning plasticizer solvent

Science

It functions by dissolving other substances, enhancing flexibility, or binding metal ions. Upon systemic absorption, it rapidly hydrolyzes into ethanol and the toxic oxalate anion, responsible for its systemic toxicity.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Generally stable, but susceptible to hydrolysis, particularly at pH 4 at 35°C with a half-life of 0.5 days. It can also complex with metal ions, potentially impacting product stability and appearance.

Conflicts

  • strong oxidizing agents
  • acids
  • bases
  • reducing agents
  • caustic solutions

Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk High

Subject to EC Cosmetics Regulation restrictions due to its classification as a strong irritant causing serious eye irritation and potential skin irritation or allergic reactions. It is harmful if swallowed or in contact with skin, hydrolyzing into toxic compounds.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its high irritancy, potential for allergic reactions, and systemic toxicity upon hydrolysis, this ingredient is unsuitable for precision skincare formulations.


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