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Moumoujus

DICHLOROPHENE.

Avoid CAS 97-23-4 / ANTIMICROBIAL, DEODORANT

Dichlorophene is an antimicrobial agent primarily functioning as a bacteriocide and fungicide. Its use in cosmetics is highly restricted globally due to safety concerns.

Summary

Antimicrobial Antifungal

Science

Mechanism of Action

It acts by uncoupling oxidative phosphorylation and binding to microbial protein thiol groups. This disrupts cell membrane integrity and interferes with essential metabolic enzymes.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Dichlorophene is acidic, slowly oxidizes in air, and forms salts with alkalis. Its photolysis pathways are pH and oxygen-dependent.

Conflicts

  • strong oxidizing agents
  • strong bases

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
0.5%
Sensitization risk Moderate

The CIR found insufficient safety data for cosmetics. Europe limits its concentration to 0.5%, Japan prohibits it, and the EPA warns of developmental toxicity.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Despite its antimicrobial properties, Dichlorophene is widely restricted or prohibited in cosmetics due to significant safety concerns, including potential for sensitization and developmental toxicity.

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