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DECAHYDROCYCLODODECAOXAZOLE.

Questionable CAS 38303-23-0 / PERFUMING

Decahydrocyclododecaoxazole functions primarily as a fragrance or perfuming agent within cosmetic formulations. Current research provides no identified mechanism of action for direct skincare benefits. Its safety profile is complex, with some regulatory bodies classifying it as a potential irritant, while others report no specific hazards.

Fragrance Perfuming agent

Science

This compound's sole role in cosmetic formulations is to impart fragrance. Scientific literature currently provides no evidence of direct beneficial mechanisms on the skin, including properties related to hydration, cellular regeneration, or anti-inflammatory responses.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Decahydrocyclododecaoxazole is characterized by its insolubility in water and solubility in alcohol, indicative of its lipophilic nature with an estimated logP (o/w) of 4.343. Specific optimal pH ranges for its stability have not been precisely determined.


Safety

CIR Status
Insufficient data
Sensitization risk Moderate

The European Chemicals Agency (ECHA) C&L Inventory lists Decahydrocyclododecaoxazole with hazard statements H315 (Causes skin irritation) and H319 (Causes serious eye irritation). Conversely, The Good Scents Company reports no GHS classifications for this ingredient. The Cosmetic Ingredient Review (CIR) has classified its data as insufficient for a full safety assessment.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Given its primary role as a fragrance agent without any demonstrated skincare benefits and conflicting safety data concerning potential irritation, its inclusion in precision skincare formulations is questionable.


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