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Moumoujus

DEA-ISOSTEARATE.

Avoid CAS 93920-28-6 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

DEA-ISOSTEARATE is a synthetic compound formed as a salt of isostearic acid and diethanolamine (DEA), utilized as a versatile surfactant and emulsifier. It aids in blending immiscible phases, stabilizes foam, and imparts conditioning and lubricating properties to formulations.

Summary

Surfactant Emulsifier pH Adjuster Lubricant Conditioning Agent Foam Stabilizer Thickening Agent

Science

Mechanism of Action

As a surfactant, DEA-ISOSTEARATE effectively reduces surface tension, enabling the stable dispersion of oil and water components within an emulsion. It also functions as a pH adjuster, helping to maintain optimal product acidity or alkalinity. Furthermore, its chemical structure provides conditioning and lubricating benefits, enhancing the sensory feel of products and contributing to foam stability and viscosity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for DEA-ISOSTEARATE stability has been identified. Diethanolamine (DEA) acts as a pH adjuster within formulations. For optimal emulsification, it is generally recommended to incorporate DEA-ISOSTEARATE in the oil or melt phase, ideally alongside a suitable co-emulsifier. Potential chemical incompatibilities may arise from direct interactions with other excipients or due to reactive impurities.

Conflicts

  • Interactions with certain drug compounds or excipients
  • Reactions with impurities in excipients

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel indicates 'insufficient data' for DEA-ISOSTEARATE specifically. While 'fatty acids and fatty acid salts' (including isostearic acid) are generally deemed safe by CIR when non-irritating, DEA-ISOSTEARATE contains Diethanolamine (DEA), which introduces specific safety considerations. A 1998 National Toxicology Program (NTP) study linked topical DEA application to cancer in laboratory animals; however, no causal link between DEA and human cancer risk has been established. The FDA advises that consumers review ingredient statements but does not currently recommend alarm. Critically, DEA-related compounds are noted for potential contamination with nitrosamines, which are classified as possible human carcinogens.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

While offering functional benefits, DEA-ISOSTEARATE is not recommended due to insufficient safety data, its diethanolamine (DEA) component linked to animal studies concerning cancer, and the potential for nitrosamine contamination.

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