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Moumoujus

DAMNACANTHUS MAJOR PHYTOPLACENTA EXTRACT.

Valuable / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

DAMNACANTHUS MAJOR PHYTOPLACENTA EXTRACT is a botanical extract derived from the callus of the Damnacanthus major plant. It precisely delivers dual-action benefits, demonstrating significant antioxidant capabilities and promoting skin hydration through enhanced hyaluronic acid synthesis.

Summary

antioxidant moisturizing skin protecting whitening hyaluronic acid synthesis booster

Science

Mechanism of Action

This extract exhibits moisturizing efficacy via the upregulation of Phospho-extracellular signal-regulated kinase 1/2 and cAMP response element-binding protein in artificial skin models. Its antioxidant effects are mediated by the upregulation of phospho-NFκB repressing factor in human epidermal keratinocytes (HaCaT cells). Additionally, anthraquinone series substances within the plant are associated with antioxidant and potential skin brightening actions.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–0.06%
Optimal

N/A

Key findings

  1. 01 Demonstrated a distinct antioxidant effect (over 600 μg/mL) in an artificial skin alternative.
  2. 02 Showed a moisturizing effect (over 125 μg/mL) using an artificial skin alternative.
  3. 03 Promoted hyaluronic acid (HA) synthesis in fibroblasts and enhanced HA content at concentrations up to 100 μg/mL (0.01%), with no observed cytotoxicity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

Comprehensive oral, dermal, and inhalation toxicity assessments for Damnacanthus major branch/leaf extract are currently not determined. No GHS classification or hazard statements have been established. However, testing on artificial skin models indicated no phototoxicity at concentrations up to 0.1% (1 mg/mL).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

With demonstrated in-vitro efficacy in antioxidant defense, moisturizing, and hyaluronic acid promotion at low concentrations, this extract presents as a valuable active ingredient for skin health, pending further comprehensive safety assessments.

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