Science
Mechanism of Action
The extract operates through a multifaceted biological approach: it disrupts the cell membranes of fungal pathogens like Candida albicans and inhibits the growth of Aspergillus niger. On a cellular level, it acts as a free radical scavenger and downregulates the expression of Matrix Metalloproteinase-2 (MMP-2), a key enzyme in collagen degradation, thereby mitigating signs of environmental aging and cellular senescence.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated 80% growth inhibition of Aspergillus niger at concentrations as low as 400 mg/L (0.04%).
- 02 Significant antibiofilm and antifungal activity against clinical Candida strains at 256 µg/mL.
- 03 Cytoprotective effects observed in fibroblast cells, showing a reduction in doxorubicin-induced senescence.
Transparency
Dusting Analysis
Due to its potent aromatic profile and primary use as a fragrance or masking agent, this ingredient is often included in sub-therapeutic 'label-claim' amounts. For physiological benefits such as oil regulation or antimicrobial support, concentrations should align closer to the 0.04% threshold identified in inhibitory studies.
The Formula
Formulation
Stability
Optimal stability in nanoemulsions is achieved with a Hydrophilic-Lipophilic Balance (HLB) of 14; particle size is temperature-sensitive, expanding from 58nm at 4°C to 140nm at 25°C.
Synergies
- Citronellal
- Antioxidants
Safety
Safety Profile
Classified as GRAS (Generally Recognized As Safe) by the FDA for food use. While ECHA reports limited evidence of dermal toxicity, botanical extracts containing essential oil components can be potential allergens for highly reactive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An excellent precision ingredient for oily and congestion-prone skin types looking for botanical oil regulation and microbial balance.
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