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Moumoujus

CYCLOHEXYLAMINE.

Avoid CAS 108-91-8 / ANTICORROSIVE, BUFFERING

Cyclohexylamine is an organic compound historically recognized for its ability to function as a weak base, primarily utilized to adjust and buffer the pH of cosmetic formulations. Despite its past applications, it is now globally banned in cosmetic products due to significant safety concerns.

Summary

pH adjuster buffering agent

Science

Mechanism of Action

This compound acts as a weak base, enabling it to modulate and maintain the pH balance within formulations by neutralizing acidic components or providing hydroxyl ions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 9.6 – 11.6
0 7 14

Stability

Cyclohexylamine functions as a weak base with a pKa of 10.64 in aqueous solutions at 25°C, providing buffer capacity within the alkaline pH range of 9.6 to 11.6.

Conflicts

  • strong oxidizers (such as chlorine, bromine, and fluorine)
  • strong acids (such as hydrochloric, sulfuric, and nitric)
  • acid chlorides
  • acid anhydrides

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0%
Sensitization risk High

Cyclohexylamine is classified as an extremely hazardous substance due to its corrosive nature, which can cause severe burns to the skin and eyes. Regulatory authorities have officially banned its intentional addition to cosmetic products, effective January 1, 2027, citing significant safety concerns, particularly for individuals with sensitive skin. The FDA has not granted it Generally Recognized As Safe (GRAS) status for direct food contact. Its permissible use in industrial contexts, such as boiler water additives, is strictly limited to 10 ppm, with outright prohibition in direct milk and dairy processing.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Cyclohexylamine is an extremely hazardous, corrosive substance universally banned in cosmetic products due to severe safety concerns, rendering it entirely unsuitable for any skincare formulations.

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