Science
Mechanism of Action
As a non-polar solvent, Cyclohexane efficiently interacts with and strips away the skin's essential lipid components. This powerful defatting action compromises the integrity of the skin barrier, leading to significant irritation, dehydration, and potentially structural damage such as cracking.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Cyclohexane is a liquid solvent and does not present a 'dusting' concern in the context of solid ingredients precipitating or leaving residue. Its primary risks are associated with direct skin contact and flammability.
The Formula
Formulation
Stability
Cyclohexane is a highly flammable liquid and vapor (H225). It is essential to store and handle it away from heat, hot surfaces, sparks, open flames, and other ignition sources. It is classified as a non-corrosive liquid.
Conflicts
- Ignition sources (heat, sparks, open flames)
- Certain rubber materials (can cause breakdown of polymer chains, decreased elasticity, brittleness, cracking, discoloration, swelling)
Safety
Safety Profile
Cyclohexane has not undergone a specific cosmetic ingredient review by the Cosmetic Ingredient Review (CIR) or the SCCS for direct use in cosmetic products. It is classified under EU regulations (H315) as causing skin irritation. The Environmental Working Group (EWG) also flags it with a high concern for irritation across skin, eyes, or lungs. Occupational exposure standards for airborne concentrations are set at a time-weighted average (TWA) of 100 ppm (350 mg/m³) and a short-term exposure limit (STEL) of 300 ppm (1050 mg/m³).
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its potent defatting and highly irritant properties, Cyclohexane is unequivocally unsuitable for direct application in skincare formulations and should be avoided.
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References
Sources