Science
Mechanism of Action
This extract contains a complex array of compounds, including bitter principles (e.g., angosturin), alkaloids (e.g., galipine, cusparine), a volatile oil, and a glucoside. While specific dermatological mechanisms for Cusparia febrifuga bark extract are not definitively established, bark extracts in general are known to exhibit antioxidant, anti-inflammatory, and antimicrobial activities, suggesting a potential role in protecting skin against oxidative stress and supporting barrier health.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The ingredient 'Angostura, Extract (Galipea officinalis Hancock)', a synonym, is listed as Generally Recognized As Safe (GRAS) by the FDA for use as a flavor agent in food. However, dermal toxicity for Cusparia febrifuga bark extract has not been determined. There is no specific Cosmetic Ingredient Review (CIR) Expert Panel safety assessment for this ingredient in cosmetic applications, indicating a current lack of comprehensive safety data for topical use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its traditional internal uses and theoretical beneficial compounds, the lack of specific clinical efficacy studies for skin, undetermined dermal toxicity, and 'not reviewed' CIR status mean Cusparia febrifuga bark extract currently lacks sufficient data for a definitive cosmetic recommendation.
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References
Sources