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Moumoujus

CUMINUM CYMINUM SEED OIL.

Questionable CAS 84775-51-9 -- 8014-13-9 / FRAGRANCE, PERFUMING, TONIC

Cuminum Cyminum Seed Oil is a potent botanical extract recognized for its broad-spectrum antimicrobial, anti-inflammatory, and antioxidant properties. It has shown promise in regulating sebum production, promoting wound healing, and contributing to a more even skin tone through melanin inhibition. However, its application in skincare requires precise formulation due to high irritancy and phototoxic potential.

Summary

Antimicrobial Antibacterial Antifungal Antiviral Anti-inflammatory Antioxidant Wound Healing Melanin Inhibition Sebum Regulation Masking Agent Perfuming Agent Tonic

Science

Mechanism of Action

Cuminum Cyminum Seed Oil exerts its effects by disrupting microbial cell membranes, inhibiting efflux pumps, and interfering with quorum sensing and biofilm formation, contributing to its antimicrobial, anti-fungal, and antiviral properties. Its anti-inflammatory and antioxidant activities involve scavenging free radicals and reducing oxidative stress. The oil can also inhibit tyrosinase, a key enzyme in melanin production, and promote wound healing by stimulating collagen production and enhancing antioxidant enzyme activity. Additionally, it aids in controlling oil production and balancing excess sebum due to its high Vitamin E content.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Cuminum Cyminum Seed Oil is highly prone to degradation, tending to darken upon aging. It is significantly sensitive to daylight, air, moisture, metals, and strong alkalis. Terpenes present in the raw material can polymerize when oxidized, further compromising its stability.

Conflicts

  • strong alkalis
  • UV light (due to significant phototoxic effects)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.4%
Sensitization risk High

While classified as Generally Recognized As Safe (GRAS) by the FDA for its use as a flavoring agent, its cosmetic application is strictly regulated by the International Fragrance Association (IFRA) due to phototoxicity, limiting its maximum concentration to 0.4% in most leave-on products, including face, body, and lip applications. It is also listed as a restricted substance (III/156) in the EU Cosmetics Regulation. The oil is considered an irritant to skin and eyes, and a dermal and respiratory sensitizer, with potential user exposure concerns for estragole and dillapiole. It must always be thoroughly diluted for topical application, and patch testing is strongly recommended prior to use due to potential skin sensitivity and allergic reactions.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Despite promising in-vitro and animal studies suggesting various skin benefits, the significant safety concerns regarding high irritancy, phototoxicity, and strict concentration limits make Cuminum Cyminum Seed Oil a questionable ingredient for precision skincare formulations.

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