CRYPTOCOCCUS/FILOBASIDIELLA/GRAPE EXTRACT FERMENT LEES.

The inclusion of 'Cryptococcus' and 'Filobasidiella' in the ingredient name raises significant safety concerns. Research indicates that species such as *Cryptococcus neoformans* are recognized human fungal pathogens capable of causing serious infections. No specific safety assessments for this combined ingredient have been conducted by cosmetic regulatory bodies like CIR, SCCS, or FDA. While general grape and yeast-derived ingredients have typically received favorable safety assessments, these do not extend to this specific combination, particularly given the association with potentially pathogenic organisms. Without explicit verification of the specific non-pathogenic strains used and robust processing methods to ensure complete safety, this ingredient carries a high degree of unknown risk for cosmetic application.