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CRYPTOCARYA CRASSINERVIA BARK OIL.

Insufficient Data / ANTIMICROBIAL, FRAGRANCE

An aromatic essential oil steam-distilled from the bark of the Cryptocarya crassinervia tree, traditionally valued for its therapeutic and antimicrobial properties. It serves as a multifunctional botanical extract that combines natural fragrance with bioactive potential for skin-soothing and protective formulations.

Antioxidant Anti-inflammatory Antimicrobial Fragrance

Science

This oil functions primarily through a rich profile of phytochemicals that provide high radical scavenging activity, effectively neutralizing oxidative stress markers like DPPH and ABTS. On a cellular level, it exerts anti-inflammatory effects by inhibiting the production of nitric oxide in macrophages, while its antimicrobial components disrupt the cell membranes of various bacterial and fungal pathogens.


Research

Medium confidence
Effective range 1.28–50%
Optimal

N/A

Key findings

  1. 01 In vitro DPPH and ABTS assays demonstrated potent antioxidant scavenging at concentrations between 1.28 and 6.97 µg/mL.
  2. 02 Inhibition of 93% of nitric oxide production in RAW 264.7 macrophages was observed at a 50 µg/mL concentration.
  3. 03 MIC values ranging from 19.0 to 36.0 µg/mL indicate broad-spectrum antimicrobial activity against S. aureus and H. pylori.

Transparency

Commonly dusted
Min. effective
0.01%
Red flag below
0.005%

Because it is an essential oil with potent aromatic properties, it is frequently used at trace levels (under 0.01%) for scent rather than at the micro-gram concentrations required for verified antioxidant or anti-inflammatory therapeutic action.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an essential oil, it is prone to oxidation; should be stored in amber glass and protected from direct UV exposure.

Synergies

  • Tocopherol
  • Carrier oils
  • Other botanical antioxidants

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While related species like Massoia bark are food-grade, bark-derived essential oils contain concentrated volatiles that may cause sensitization in reactive individuals. CIR data is currently unavailable for this specific species.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

A promising botanical with verified antioxidant and anti-inflammatory potential in vitro, though its long-term safety profile and precise dermal efficacy lack robust human clinical trials.


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