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Moumoujus

CROTON ELUTERIA OIL.

Questionable CAS 84836-99-7 / PERFUMING

Croton Eluteria Oil, also known as Cascarilla Bark Oil, is a botanical extract recognized for its diverse actions on the skin. It exhibits significant antimicrobial and antioxidant properties, while also contributing to a soothing effect, making it a multifaceted ingredient for targeted skincare applications.

Summary

Antimicrobial Antioxidant Soothing Agent

Science

Mechanism of Action

This oil operates through several key mechanisms. It demonstrates potent antimicrobial activity against various pathogens, including Gram-positive bacteria like Micrococcus luteus, yeasts such as Candida krusei, and molds, which assists in managing skin conditions associated with these microorganisms. Furthermore, it offers robust antioxidant protection by mitigating oxidative stress. The presence of terpenoids is thought to confer skin-calming and anti-itch benefits, potentially alleviating minor irritations when appropriately diluted.

Research

Clinical Evidence

Medium confidence
Effective range 0.746–0.946%
Optimal

N/A

Key findings

  1. 01 Demonstrated antimicrobial activity against Micrococcus luteus at a minimum inhibitory concentration of 0.746% (7.46 µL/mL).
  2. 02 Demonstrated antimicrobial activity against Candida krusei at a minimum inhibitory concentration of 0.946% (9.46 µL/mL).
  3. 03 Exhibited a marked antioxidant capacity with 81.1% inhibition in a DPPH radical-scavenging assay.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This oil is soluble in alcohol and other oils but shows practical insolubility in water (approximately 96.99 mg/L at 25 °C). It is a flammable liquid and vapor but generally non-discoloring in most formulation bases. For optimal stability, it should be stored in sealed, dark glass vials at low temperatures.

Conflicts

  • Known sensitizers (carvone, eugenol)
  • Potential animal carcinogen (methyl eugenol)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
4%
Sensitization risk Moderate

While the FDA classifies 'Cascarilla Bark, Oil (Croton spp.)' as Generally Recognized As Safe (GRAS) for food use, its safety for cosmetic applications has not been reviewed by the CIR. IFRA guidelines recommend usage levels up to 4.0000% for fragrance concentrates. However, the oil contains restricted components: carvone (<0.10%) and eugenol (0.4%), both noted for sensitization risk, and methyl eugenol (<1.00%), a potential animal carcinogen. Safety Data Sheets explicitly warn that it 'May cause an allergic skin reaction'.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Despite demonstrating antimicrobial, antioxidant, and potential soothing benefits, the unreviewed CIR status for cosmetic use, medium irritancy, and presence of restricted sensitizing components warrant a cautious approach for precision skincare formulations.

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