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Moumoujus

COLEUS BARBATUS ROOT EXTRACT.

Valuable CAS 223748-52-5 / SKIN CONDITIONING

A botanical powerhouse rich in forskolin, this extract functions as a biological architect for the skin, stimulating cellular messengers to enhance structural integrity. It is primarily utilized for its unique ability to modulate skin metabolism, offering significant benefits for barrier repair and texture refinement.

Summary

Skin Conditioning Humectant Emollient Metabolic Stimulant Anti-inflammatory

Science

Mechanism of Action

Coleus Barbatus Root Extract operates by elevating levels of cyclic adenosine monophosphate (cAMP) within skin cells. This increase in cAMP acts as a signal for various physiological processes: it promotes lipolysis to reduce puffiness, stimulates keratinocyte differentiation for a stronger barrier, and boosts microcirculation. Additionally, it helps shield the skin from UV-induced DNA damage by activating natural protective pathways.

Research

Clinical Evidence

Medium confidence
Effective range 0.05–0.1%
Optimal

0.1%

Key findings

  1. 01 Demonstrated efficacy in barrier repair and cellulite reduction at concentrations of 0.05% to 0.1%.
  2. 02 In vivo testing indicates a visible reduction in tissue puffiness and uneven skin texture.
  3. 03 Research confirms the ability of its bioactive forskolin to provide pre-damage shielding against UV light exposure.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Because it is effective at very low concentrations (starting at 0.05%), many brands include it at 'trace' amounts below 0.01% simply for label claims, which fails to trigger the necessary cAMP response for metabolic benefits.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract shows versatility in both water and oil-based systems; however, specific pH stability ranges are not yet widely established in clinical literature.

Synergies

  • UV filters
  • Antioxidants
  • Caffeine

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Low

While topical use is generally well-tolerated with low irritancy, oral consumption is cautioned against during pregnancy; therefore, we recommend consulting a physician for topical use during pregnancy as a precaution.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A high-precision metabolic activator that excels in texture refinement and barrier fortification when formulated at active concentrations.

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