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COCODIMONIUM HYDROXYPROPYL HYDROLYZED CASEIN.

Valuable / ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

This quaternized derivative of hydrolyzed casein functions primarily as a potent skin conditioning agent, helping to maintain skin health. It provides essential hydration and conditioning benefits, while also offering advanced properties like reducing facial pigmentation by targeting AGEs, alongside anti-inflammatory and antibacterial effects.

Skin Conditioning Antistatic Hair Conditioning Anti-pigmentation Anti-inflammatory Antibacterial

Science

COCODIMONIUM HYDROXYPROPYL HYDROLYZED CASEIN forms a protective layer on the skin, delivering hydration and conditioning. Its casein-derived peptides actively reduce facial pigmentation by diminishing advanced glycation end products (AGEs). Additionally, it possesses anti-inflammatory properties and can exert antibacterial effects by disrupting bacterial membranes, inhibiting cell wall synthesis, and interfering with bacterial metabolism. The quaternized structure also provides antistatic benefits.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 2021 study demonstrated that casein hydrolysate effectively reduces facial pigmentation by lowering skin accumulation of advanced glycation end products (AGEs) in non-hypertensive individuals.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

This ingredient exhibits optimal stability and solubility within a pH range of 6 to 8, with maximum stability noted at pH 8. It demonstrates reduced stability and can precipitate or flocculate around its isoelectric point of pH 4.6. Formulations below pH 3 carry a high risk of chain hydrolysis.


Safety

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

The CIR Expert Panel deems bovine milk proteins and their derivatives, including Hydrolyzed Casein, safe for use at current concentrations. Human safety tests showed no dermal irritation or sensitization at concentrations as high as 30%. The FDA recognizes bovine milk as Generally Recognized As Safe (GRAS) for food applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This ingredient is a valuable multi-functional protein derivative offering significant skin conditioning, anti-pigmentation, anti-inflammatory, and antibacterial benefits, with a strong safety profile and broad skin compatibility.


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