Science
Mechanism of Action
Cocamine and its oxide derivatives function by reducing the surface tension of water, allowing for the efficient suspension and removal of oil-based impurities and environmental debris. Beyond cleansing, it acts as a hydrotrope to improve the solubility of other formulation components and provides antistatic conditioning by neutralizing surface charges on skin and hair.
Research
Clinical Evidence
Medium confidence2.5%
Key findings
- 01 Human Repeat Insult Patch Tests (HRIPT) on related PEG-15 Cocamine at concentrations up to 2.9% demonstrated no evidence of sensitization or phototoxicity.
- 02 Safety assessments of related amine oxides indicate that a 5% concentration is a non-irritant, while extreme concentrations of 81.5% are required to produce moderate dermal irritation.
Transparency
Dusting Analysis
As a functional surfactant and viscosity builder, Cocamine is rarely used for 'label claims' and is typically included at levels necessary for formula stability and performance.
The Formula
Formulation
Stability
Highly stable in both acidic and alkaline environments; certain grades remain functional even in the presence of strong oxidizers like bleach. pH levels significantly influence the final viscosity of the system.
Synergies
- Anionic surfactants
- Conditioning polymers
Safety
Safety Profile
The CIR Expert Panel supports safety in rinse-off applications up to 4%. OECD data confirms that amine oxides are non-genotoxic and do not present reproductive or developmental toxicity concerns.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An efficient and safe multi-functional surfactant that provides essential texture and cleansing properties to rinse-off skincare formulations.
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