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Moumoujus

CITRUS SPECIES LEAF OIL.

Avoid CAS 94266-47-4 / PERFUMING

Citrus Species Leaf Oil is an essential oil derived from the leaves of various citrus plants, valued for its in vitro antioxidant and potential antimicrobial properties. It contains active compounds such as Citral and phenolic compounds, which are investigated for their capacity to neutralize free radicals and inhibit microbial growth.

Summary

Antioxidant Antimicrobial Perfuming Anti-inflammatory (potential)

Science

Mechanism of Action

This ingredient functions as an antioxidant by scavenging excess free radicals like hydroxyl, peroxide, and super oxygen radicals. Its component, Citral, demonstrates broad-spectrum antibacterial and fungicidal activity by disrupting microbial cell membranes and metabolic processes. Phenolic compounds further contribute bacteriostatic and fungistatic effects through structural damage to fungal cells. Citral also exhibits potential anti-inflammatory properties.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Citral, a major component, is highly sensitive to degradation by air and light. It is also unstable in both alkaline and strong acidic environments. Products formulated with Citrus Species Leaf Oil have been reported within a pH range of 6-9.

Conflicts

  • Alkalies
  • Strong oxidizing agents
  • Strong acids
  • Light
  • Air

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
15%
Sensitization risk High

The International Fragrance Association (IFRA) restricts the total concentration of bergapten (5-methoxypsoralen), a constituent of Citrus Species Leaf Oil, to a maximum of 15 ppm in final leave-on products when combined with other citrus oils. Citral, another common component, while generally recognized as safe at low concentrations, poses a significant risk of skin and respiratory irritation, particularly with prolonged or concentrated exposure. It is categorized as a mild sensitizer and can induce allergic contact dermatitis in sensitive individuals. A human patch test demonstrated that Citral at a 32% concentration was highly irritating. European Commission regulations mandate its indication in ingredient lists if concentrations exceed 0.001% in leave-on products or 0.01% in rinse-off products. Paula's Choice notes a high likelihood of irritation, inflammation, or dryness, which may intensify when combined with other problematic ingredients.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Despite its in vitro antioxidant and antimicrobial activities, Citrus Species Leaf Oil presents a high risk of skin irritation and sensitization due to its Citral content and an 'Avoid' rating from INCIDecoder, rendering it unsuitable for precision skincare formulations.

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