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Moumoujus

CITRUS RETICULATA FRUIT EXTRACT.

Valuable CAS 8008-31-9 / SKIN PROTECTING

Commonly known as Mandarin Orange or Tangerine extract, this botanical powerhouse provides a multi-targeted approach to skin health, combining potent antioxidant protection with advanced neuro-calming properties. It is specifically valued in precision skincare for its ability to modulate the skin's sensory receptors, making it a premier choice for reactive and stressed complexions.

Summary

Skin protecting Anti-inflammatory Antioxidant Brightening Soothing

Science

Mechanism of Action

This extract operates through a sophisticated dual mechanism: it inhibits the activation and protein expression of TRPV1 (Transient Receptor Potential Vanilloid 1) receptors, effectively reducing the calcium ion influx that triggers stinging and discomfort in sensitive skin. Simultaneously, its high concentration of flavonoids and Vitamin C provides antioxidant defense while suppressing collagenase and elastase enzymes to preserve the skin's structural matrix.

Research

Clinical Evidence

High confidence
Effective range 0.25–4%
Optimal

1%

Key findings

  1. 01 In vitro data demonstrates that concentrations as low as 0.25% successfully suppress TRPV1 protein expression induced by chemical irritants like lactic acid.
  2. 02 Clinical in vivo testing showed that topical application provides immediate relief from lactic acid-induced stinging and significantly improves overall skin tolerance after 7 days of consistent use.
  3. 03 In vitro assays between 1-4% confirmed the extract's ability to inhibit TRPV1 activation triggered by common triggers such as phenoxyethanol and nicotinamide.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.25%
Red flag below
0.1%

While many mass-market brands include this extract at symbolic 'label-claim' levels (often below 0.1%) for its citrus association, clinical efficacy for skin-soothing benefits requires a minimum concentration of 0.25% to interact with TRPV1 receptors effectively.

The Formula

Formulation

Solubility
Water
Optimal pH 3.4 – 5.5
0 7 14

Stability

Optimal stability is maintained in cool, light-protected environments; the extract remains viable for up to 24 months when stored correctly.

Synergies

  • Vitamin C
  • Lactic Acid
  • Nicotinamide
  • Antioxidants

Conflicts

  • High-dose phototoxic compounds (5-MOP must be restricted)

Safety

Safety Profile

CIR Status
Safe as used with restrictions
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Safety is contingent on the removal of phototoxic furocoumarins; leave-on products must contain less than 15 ppm of 5-methoxypsoralen (5-MOP). It is generally recognized as safe (GRAS) by the FDA.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A high-performance botanical that bridges the gap between traditional antioxidant protection and modern neuro-cosmetic soothing.

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