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CITRONELLAL.

Questionable CAS 106-23-0 / FRAGRANCE

Citronellal is a naturally occurring acyclic monoterpenoid aldehyde, widely recognized for its characteristic lemon-rose scent. Primarily extracted from essential oils such as citronella and lemongrass, it functions predominantly as a fragrance compound within cosmetic formulations.

Fragrance Perfuming

Science

In skincare, Citronellal's primary mechanism is olfactory, contributing to the sensory profile of a product. While it exhibits insect-repelling properties and some mild antimicrobial activity in specific contexts, there is limited clinical evidence supporting direct beneficial biological mechanisms on human skin cells relevant to precision skincare outcomes.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Commonly dusted
Min. effective
0.001%
Red flag below
1%

Citronellal is classified as a fragrance allergen by regulatory bodies such as the EU SCCS. It must be listed individually on ingredient labels when its concentration exceeds 0.001% in leave-on products or 0.01% in rinse-off products. Concentrations above 1.0% are generally considered to significantly elevate the risk of skin sensitization for susceptible individuals.


The Formula

Solubility
Oil
Optimal pH 3 – 7
0 7 14

Stability

Citronellal is highly susceptible to oxidation when exposed to air, light, and heat, which can lead to the formation of more potent sensitizers like hydroperoxides. Effective formulation requires the incorporation of antioxidants and packaging that minimizes light and air exposure to maintain stability.

Conflicts

  • Strong oxidizing agents
  • Extreme pH conditions (highly acidic or alkaline environments)

Safety

CIR Status
Reviewed; deemed safe for cosmetic use within established concentration limits, provided oxidation is minimized.
Max tested
0.5%
Pregnancy
Safe
Sensitization risk Moderate

Despite CIR's general safety assessment under specific conditions, Citronellal poses a moderate risk of sensitization, particularly for individuals with fragrance allergies or when oxidized. Prudent use dictates minimal effective concentrations and robust antioxidant protection.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Questionable

Citronellal's role in skincare is primarily for fragrance, but its moderate sensitization risk suggests a questionable utility for precision skincare formulations prioritizing skin health over scent.


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