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CIS-JASMONE.

Insufficient Data CAS 488-10-8 / PERFUMING

Cis-Jasmone is a plant-derived jasmonate, a class of hormones pivotal in botanical stress responses, wound repair, and defense mechanisms. In skincare, this molecule, or related jasmonate analogs, demonstrate potential benefits for enhancing epidermal hydration, promoting skin thickness, and mitigating visible signs of aging such as wrinkles and photoaging.

fragrance ingredient skin conditioning anti-aging

Science

As a member of the jasmonate family, Cis-Jasmone is theorized to influence cellular pathways akin to its role in plant protection and regeneration. While the precise mechanisms of Cis-Jasmone on human skin require further elucidation, the broader jasmonate class is recognized for its capacity to stimulate epidermal hyaluronic acid synthesis and increase skin density, both crucial for maintaining hydration and structural integrity.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 3 – 10
0 7 14

Stability

Cis-Jasmone exhibits robust stability within a pH range of 3.0 to 10.0. It is unstable and susceptible to degradation in highly acidic environments (e.g., pH 2.0) and strongly alkaline solutions (e.g., pH 11.0 to 14.0).

Conflicts

  • Strong acidic products (e.g., pH 2 acid cleaners)
  • Very alkaline detergents and liquid bleach (pH 11, 14)
  • May damage weak plastics, paints, and greases if in direct contact

Safety

CIR Status
Safe as used
Sensitization risk Unknown

A toxicologic and dermatologic review determined an adequate Margin of Exposure (MOE) for Cis-Jasmone regarding repeated dose toxicity at current usage levels. It was also found to be negative for clastogenicity in human cells, suggesting no genotoxic concerns. The FDA has categorized it as safe for general or specific, limited use in food applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While demonstrating a favorable safety profile, direct clinical data specifically validating Cis-Jasmone's efficacy for skin benefits are currently limited, with most potential actions inferred from related jasmonate compounds.


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