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CIS-4-DECENAL.

Questionable CAS 21662-09-9 / PERFUMING

Cis-4-Decenal is an aldehyde renowned for its potent citrus and aldehydic aroma, widely utilized in perfumery and as a flavor enhancer. Beyond its aromatic properties, research indicates potential antimicrobial activity against specific bacteria and fungi.

Fragrance Antimicrobial Agent

Science

This compound primarily engages olfactory receptors to impart its distinctive fresh, citrusy scent. It also demonstrates an ability to inhibit the growth of certain microorganisms, suggesting a role as a potential antimicrobial agent on the skin's surface.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Studies propose potential antimicrobial effects against select bacterial and fungal species, positioning it as a candidate for preservative applications. However, specific effective concentrations for skin-based antimicrobial benefits are not yet established.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Cis-4-Decenal exhibits a propensity for instability or oxidation and is frequently stabilized with antioxidants like synthetic alpha-tocopherol in commercial preparations. Compatibility testing is essential to ensure formulation stability and preserve performance.


Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel typically defers review of ingredients solely functioning as fragrances to the Research Institute for Fragrance Materials (RIFM). While FEMA (Flavor and Extract Manufacturers Association) classifies it as Generally Recognized As Safe (GRAS) for flavoring, concentrated forms can cause skin and serious eye irritation. However, a 1% solution has been documented to cause no irritation or sensitization in human experience.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Questionable

While a valuable fragrance component with documented low irritation at cosmetic concentrations and potential antimicrobial properties, its efficacy as a primary skincare active requires further quantified research specific to skin applications.


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