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CIS-3-HEXENYL PROPIONATE.

Questionable CAS 33467-74-2 / PERFUMING

CIS-3-HEXENYL PROPIONATE is a synthetic ester primarily utilized in skincare and cosmetic formulations for its distinct fresh, green, and fruity aromatic profile. It serves exclusively as a fragrance component to enhance product sensory appeal.

perfuming agent

Science

This compound functions by imparting a pleasant scent to products, thereby improving the user's sensory experience. It does not engage in any biological pathways within the skin or body, offering no therapeutic skin benefits.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted
Red flag below
0.2%

While a maximum use concentration of 0.20% is generally advised for safety, this ingredient is known to cause irritation in a notable percentage of reports, indicating it may not be suitable for all skin types. Its inclusion serves solely olfactory purposes, without contributing to skin health.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

CIS-3-HEXENYL PROPIONATE exhibits good stability when formulated according to specifications. However, its integrity is significantly compromised by temperatures exceeding 40°C, necessitating careful heat management during processing and storage.

Conflicts

  • strong oxidizing agents
  • heat above 40C

Safety

CIR Status
Not reviewed
Max tested
0.2%
Sensitization risk Moderate

Generally considered safe within recommended limits, a patch test is advised prior to widespread use. GHS classification highlights potential for skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335), observed in 19.8% of reports. Acute toxicity tests indicate a low systemic toxicity profile (LD50-Oral-Rat >5,000 mg/kg, LD50-Dermal-Rabbit >5,000 mg/kg). Safety Data Sheets recommend thorough washing after handling and avoiding contact with skin and eyes. It is listed as a Fragrance Ingredient by IFRA.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

CIS-3-HEXENYL PROPIONATE is a fragrance additive offering no therapeutic skin benefits and presenting a moderate risk of skin and eye irritation, particularly for sensitive individuals, making its inclusion questionable for precision skincare.


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