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Moumoujus

CIS-3-HEPTENYL ACETATE.

Questionable CAS 1576-78-9 / PERFUMING

CIS-3-HEPTENYL ACETATE is a synthetic aroma compound primarily incorporated into cosmetic and personal care products for its distinct perfuming qualities. While it imparts no therapeutic benefits to the skin, its use is carefully governed due to a recognized potential for dermal sensitization.

Summary

perfuming

Science

Mechanism of Action

This compound functions exclusively as a fragrance component, enhancing the sensory profile of formulations. It does not interact with biological pathways in the skin or body to deliver functional improvements or therapeutic effects.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted
Red flag below
0.46%

As a pure perfuming agent, CIS-3-HEPTENYL ACETATE offers no active benefits. Its use is strictly regulated by IFRA, with maximum concentrations set due to dermal sensitization concerns, ensuring precise, limited incorporation rather than liberal 'dusting'.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.46%
Sensitization risk High

CIS-3-HEPTENYL ACETATE is classified as a skin sensitizer, with a No Expected Sensitization Induction Level (NESIL) of 1000 µg/cm². Its use in cosmetic products is restricted by IFRA due to concerns regarding dermal sensitization and systemic toxicity. Maximum acceptable concentrations vary by product category, for instance, 0.077% in lip products and up to 0.46% in products applied to the face/body using fingertips. It is not expected to be genotoxic, and repeated dose toxicity showed a No Observed Adverse Effect Level (NOAEL) of 333 mg/kg/day.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While serving solely as a perfuming agent, CIS-3-HEPTENYL ACETATE carries a significant risk of dermal sensitization, making its inclusion in precision skincare questionable for optimal skin health.

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