Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

CINNAMOMUM CASSIA WOOD EXTRACT.

Questionable CAS 84961-46-6 / PERFUMING

Cinnamomum Cassia Wood Extract is primarily valued for its aromatic qualities within cosmetic formulations. While studies on the closely related Cinnamomum Cassia Bark Extract indicate a spectrum of potential dermatological benefits, including anti-inflammatory and antioxidant properties, its direct therapeutic efficacy as a wood extract requires further specific investigation.

Summary

fragrance anti-inflammatory (from bark extract research) antioxidant (from bark extract research) antibacterial (from bark extract research) sebum regulation (from bark extract research) pore cleansing (from bark extract research) skin barrier support (from bark extract research) hydration (from bark extract research)

Science

Mechanism of Action

The primary function identified for Cinnamomum Cassia Wood Extract is its contribution to fragrance. However, research conducted on the related Cinnamomum Cassia Bark Extract suggests broader mechanisms such as antioxidant activity by neutralizing free radicals, anti-inflammatory effects through inhibition of degranulation and suppression of inflammatory mediators, and promotion of skin microcirculation. It may also support skin barrier function by enhancing keratinocyte differentiation markers and stimulate hyaluronic acid production.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Studies on related Cinnamomum cassia Bark Extract demonstrated significant anti-inflammatory effects in vitro, inhibiting RBL-2H3 cell degranulation by 14.58% at 100 µg/mL, progressing to 95.58% at 300 µg/mL.
  2. 02 Highest anti-inflammation activity (44.35%) was observed at 400 µg/mL in related Cinnamomum cassia Bark Extract studies.
  3. 03 Animal studies (NC/Nga mice) using Cinnamomum cassia extract showed a dose-dependent suppression of inflammatory mediators (TARC, macrophage-derived chemokine, and RANTES) and inhibited the development of atopic dermatitis-like skin lesions by attenuating the T-helper 2 cell response.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

While Cinnamomum cassia essential oil is FDA recognized as safe, the European Cosmetics and Personal Care Products Regulation mandates careful monitoring of Cinnamomum cassia bark extract concentrations in cosmetics. This ingredient, including its essential oil and extracts, carries a notable risk of causing skin irritation, redness, itching, and potential contact dermatitis, especially for individuals with sensitive skin or existing cinnamon allergies. High oral doses in rats have indicated potential nephrotoxicity and hepatotoxicity. Patch testing is strongly recommended prior to extensive use, particularly for individuals with sensitive skin.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Primarily functioning as a fragrance, Cinnamomum Cassia Wood Extract's therapeutic benefits are largely inferred from studies on its related bark extract, carrying a medium irritancy risk that necessitates careful consideration for precision skincare formulations, especially for sensitive skin.

Related

Similar Ingredients

Finding similar ingredients…