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CINNAMOMUM CAMPHORA LINALOOLIFERUM ROOT EXTRACT.

Insufficient Data CAS 91745-89-0 / PERFUMING

Derived from the Cinnamomum Camphora Linalooliferum species, this root extract offers a multifaceted approach to skin health. It is recognized for its potential anti-inflammatory and antimicrobial properties, aiding in soothing irritation and managing blemish-causing microorganisms. Additionally, it acts as an astringent, helping to refine skin texture, and may provide antioxidant protection while supporting skin barrier function.

Summary

Anti-inflammatory Antimicrobial Astringent Antioxidant Skin Barrier Support Moisturizing Perfuming Penetration Enhancer

Science

Mechanism of Action

Cinnamomum Camphora Linalooliferum Root Extract operates through multiple pathways to support skin health. Its anti-inflammatory effects potentially soothe irritation by modulating cytokine secretion (e.g., IL-1β, IL-6, TNF-α) and controlling macrophage-mediated inflammation. It also appears to mitigate oxidative stress and suppress ERK1/2 phosphorylation, contributing to its calming action. The extract's antimicrobial activity, largely attributed to its major component linalool, helps inhibit bacterial growth, such as Staphylococcus aureus, which can contribute to blemishes. It acts as an astringent, assisting in pore tightening and textural refinement. Furthermore, it may offer antioxidant benefits against free radicals, strengthen the skin barrier, and contribute to moisturization. Some constituents may also act as carriers, potentially enhancing the skin penetration of other active ingredients.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Synergies

  • Enhanced penetration of other active ingredients

Conflicts

  • Due to the high potential for allergies associated with the linalooliferum chemotype's essential oils (e.g., Ho Wood oil), this ingredient should be formulated with caution, ensuring appropriate dilution for topical application to minimize sensitization risk.
  • Not recommended for use by pregnant individuals during the first trimester (less than 3 months) and for infants under 3 years old.

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not evaluated CINNAMOMUM CAMPHORA LINALOOLIFERUM ROOT EXTRACT specifically. However, related ingredients within the Cinnamomum Camphora Linalooliferum chemotype, such as the leaf oil, have been subject to cosmetic restrictions (EU SCCS III/84). Ingredients rich in linalool, a primary component of this chemotype, are noted by IFRA for their sensitization potential. There is no specific FDA status available. Additionally, this ingredient is contraindicated for use in early pregnancy (first trimester) and for infants under 3 years of age.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While offering a range of potential skin benefits including anti-inflammatory, antimicrobial, and antioxidant effects, its safety profile warrants caution due to the lack of specific CIR review for this extract and high sensitization potential associated with related linalool-rich compounds, making more data necessary for a definitive assessment.

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