Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CINCHONA PUBESCENS BARK EXTRACT.

Valuable CAS 97435-02-4 / SKIN CONDITIONING

Cinchona Pubescens Bark Extract, derived from the Cinchona tree, is recognized for its potent antioxidant properties and ability to condition the skin. It supports cellular protection against oxidative stress and contributes to overall skin health.

Skin conditioning Antioxidant

Science

This extract exerts significant antioxidant effects, attributed to its rich content of phenolic compounds and flavonoids, which neutralize free radicals. Beyond its antioxidant capacity, it functions as a skin conditioning agent, enhancing skin texture and appearance. While primarily noted for hair growth stimulation via the Wnt/b-catenin pathway and VEGF production, its direct mechanisms for skin regeneration and anti-aging in skincare context are largely linked to its protective antioxidant profile.


Research

Medium confidence
Effective range 0.25–1%
Optimal

1%

Key findings

  1. 01 Demonstrated the highest antioxidant activity, achieving 14.8230 ± 0.3215 µmol trolox/gr.
  2. 02 Exhibited superior antioxidant potential, yielding 13.8231 ± 0.3618 µmol trolox/gr.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Conflicts

  • Alkaline ethanol media can facilitate the precipitation of tannins present within the extract, potentially impacting formula stability and efficacy.

Safety

CIR Status
Not reviewed
Sensitization risk Low

EWG identifies this ingredient as 'Restricted' for EWG VERIFIED products without sufficient substantiation, yet rates it with a low hazard for cancer, allergies, immunotoxicity, and developmental/reproductive toxicity. While European cosmetic regulations are stringent, there is an acknowledged likelihood of irritation, which can increase when combined with other potentially problematic ingredients. INCIDecoder indicates a low irritancy potential.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

This extract offers valuable antioxidant and skin conditioning benefits, making it a promising ingredient for cellular protection and improved skin health, despite its 'not reviewed' CIR status and primary association with hair care.


Related

Finding similar ingredients…


References