Science
Mechanism of Action
As metallic silver (Argentum metallicum), CI 77820 exerts its therapeutic effects by releasing Ag+ ions. These highly active ions target a broad spectrum of pathogenic germs and microbes, effectively disrupting their multiplication, preventing infections, normalizing the skin's bacterial balance, and mitigating inflammation associated with harmful microorganisms.
Research
Clinical Evidence
Medium confidence0.1%
Key findings
- 01 Highly effective as an antibacterial and antimicrobial agent, normalizing skin flora and preventing infections, with no reported side effects at this dosage.
Transparency
Dusting Analysis
The European Scientific Committee on Consumer Safety (SCCS) has classified micron-sized particulate Silver as 'Toxic for Reproduction Category 2'. Consequently, they deem its use unsafe at concentrations up to 0.3% in leave-on cosmetic products, indicating a significant risk associated with exceeding this threshold.
The Formula
Formulation
Stability
Specific formulation parameters such as solubility, optimal pH range, and stability notes are not detailed in the available research data.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has deferred evaluation of CI 77820, noting that the FDA considers it a color additive safe for fingernail polish up to 1%, but not approved for eye-area cosmetics. Critically, the European SCCS classifies micron-sized particulate Silver as 'Toxic for Reproduction Category 2' and deems it unsafe in rinse-off products up to 0.2% and leave-on products up to 0.3%. While risks of allergy are low, as silver particles generally remain on the skin surface, a patch test is advised. Due to the 'Toxic for Reproduction Category 2' classification by SCCS, this ingredient is considered unsuitable for use during pregnancy.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite demonstrating antibacterial benefits at a precise concentration of 0.1%, CI 77820 is classified by the SCCS as 'Toxic for Reproduction Category 2' for leave-on products at concentrations up to 0.3%, rendering its inclusion in precision skincare formulations highly problematic and unadvisable.
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