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Moumoujus

CI 75170.

Optional CAS 73-40-5 / COLORANT

CI 75170, commonly known as Guanine, is a naturally derived cosmetic ingredient that imparts a distinctive white to yellowish pearl luster. It is widely incorporated into various skincare and makeup products to achieve a sophisticated iridescent and shimmering visual effect.

Summary

colorant pearlescent agent opacifying

Science

Mechanism of Action

This ingredient functions by creating a pearly, iridescent effect through the physical interaction of light. It absorbs and reflects light, generating a luminous sheen that enhances the aesthetic appeal of formulations.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

CI 75170 is utilized as a colorant and pearlescent agent, not an active ingredient subject to 'dusting' phenomena in the context of efficacy or adverse reactions.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Guanine demonstrates practical insolubility in water at neutral pH. However, its solubility markedly increases under extremely acidic or basic conditions. It can be effectively dissolved in ammonia water, caustic soda, and dilute mineral acids. It also exhibits slight solubility in ethanol and ethyl ether. The compound is stable under normal conditions but is incompatible with strong oxidizing agents, which should be avoided in formulations.

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Deferred evaluation
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has deferred evaluation, noting its safety has been comprehensively assessed by the U.S. FDA. The FDA designates Guanine as a color additive exempt from certification, affirming its safety for use in cosmetics, including products for the eye area, provided it conforms to FDA specifications. It is also approved for use in externally applied drugs. The EC Cosmetics Regulation (1223/2009 Annex IV) ensures toxicological safety for colorants like CI 75170. SkinSAFE classifies Guanine as 'Irritant Free' and safe for sensitive skin, infants, and eyelids. The Environmental Working Group (EWG) further indicates no expected organ system toxicity, persistence, or bioaccumulation concerns.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

CI 75170 is a safe, FDA-approved cosmetic colorant widely utilized for its pearlescent and opacifying properties, enhancing product aesthetics without offering direct therapeutic skin benefits.

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