Science
Mechanism of Action
CI 50420 functions by depositing its synthetic pigment molecules onto the surface of the skin or within a cosmetic matrix. This imparts a black or dark blue/purple coloration, strictly serving an aesthetic purpose without interacting with biological pathways to confer therapeutic benefits.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Nigrosin (CI 50420) demonstrates stability under standard ambient conditions. Optimal storage involves maintaining a dry environment between +5 °C and +30 °C, ensuring containers remain tightly sealed to preserve integrity.
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) generally does not assess colorants. While the Scientific Committee on Consumer Safety (SCCS) has not issued a specific opinion on CI 50420, its use in hair dye products is restricted. According to Regulation (EC) No 1272/2008, it is not classified as acutely toxic, skin corrosive/irritant, eye irritant, respiratory/skin sensitizer, germ cell mutagenic, carcinogenic, or reproductive toxicant. EWG Skin Deep indicates a low concern for cancer and allergies/immunotoxicity, a low-moderate concern for developmental/reproductive toxicity, and a moderate concern for use restrictions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
CI 50420 is an optional cosmetic colorant, providing black or dark blue/purple hues to formulations with a generally low risk profile for irritation or sensitization.
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References
Sources