Science
Mechanism of Action
As a cosmetic colorant, CI 45410 functions by absorbing and reflecting specific wavelengths of light, primarily contributing a reddish-pink pigment. Its molecular structure allows some forms to exhibit pH-dependent color changes, appearing transparent below pH 4.0 in the absence of moisture and transitioning to a deep pink above pH 4.0 when interacting with moisture.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 The Scientific Committee on Consumer Safety (SCCS) Opinion SCCS/1428/11 (2012) assessed CI 45410, finding it safe for use in oxidative hair dye formulations up to 2.0% and in non-oxidative hair dye formulations up to 0.4%. Furthermore, SCCS confirmed its non-irritating and non-sensitizing properties at concentrations typical for topical application.
Transparency
Dusting Analysis
As a cosmetic colorant, CI 45410 is not typically associated with 'dusting' concerns related to physiological skin effects or ingredient delivery at higher concentrations, unlike some active ingredients.
The Formula
Formulation
Stability
CI 45410 demonstrates robust stability in alkaline environments but will precipitate under acidic conditions. It exhibits poor resistance to light exposure, potentially leading to color degradation, yet offers good heat resistance up to 105°C. For optimal color longevity in cosmetic products, maintaining a pH range between 5 and 11 is recommended.
Conflicts
- strong oxidizing agents
- acidic conditions (leading to precipitation)
Safety
Safety Profile
CI 45410 is an FDA-approved synthetic dye for general cosmetic use, with the exception of eye products. The SCCS has deemed its use safe in hair dye formulations at maximum on-head concentrations of 2.0% (oxidative) and 0.4% (non-oxidative). Importantly, SCCS assessments confirm it is non-irritating and non-sensitizing to the skin at typical topical application concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
CI 45410 serves as a valuable and safe cosmetic colorant, providing a pink to red hue with demonstrated low irritancy and sensitization potential for topical applications within specified concentrations.
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