Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CI 45350.

Optional CAS 518-47-8 / 2321-07-5 / 6417-85-2 / COLORANT

CI 45350, also known as Fluorescein Sodium, is a highly specialized water-soluble colorant that provides a vibrant yellow to yellow-red hue. It is particularly distinguished by its unique yellow-green fluorescence, which shifts in intensity based on the pH environment of the formulation.

Colorant Fluorescent Agent

Science

Primarily utilized as a cosmetic colorant, CI 45350 works by absorbing light and re-emitting it, creating a distinctive fluorescent effect. Its visual properties are highly sensitive to pH levels; the fluorescence is most prominent in neutral or alkaline conditions and disappears when acidified, making it an excellent visual indicator in precision formulations.


Research

Low confidence
Effective range ≤0.044%
Optimal

N/A


Transparency

Not commonly dusted
Min. effective
0.01%
Red flag below
0.001%

As a potent colorant, this ingredient is used at extremely low concentrations to achieve the desired aesthetic. It is not an active ingredient, so 'dusting'—the practice of using sub-therapeutic levels of an active—is not applicable here.


The Formula

Solubility
Water
Optimal pH 7 – 9
0 7 14

Stability

Heat tolerant and stable in aqueous solutions. The characteristic fluorescence is pH-dependent, requiring a neutral to alkaline environment to be visible.

Conflicts

  • Acidic environments (loss of fluorescence)

Safety

CIR Status
Not reviewed
Max tested
0.044%
Pregnancy
Safe
Sensitization risk Low

Regulated globally; FDA certification is required (as D&C Yellow No. 7 or No. 8). Restricted to external applications only. A strict 0.044% limit applies specifically to contact lens solutions.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A safe and effective colorant for achieving specific aesthetic effects and pH-responsive visual properties in external skincare.


Related

Finding similar ingredients…