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Moumoujus

CI 18965.

Insufficient Data CAS 6359-98-4 / COLORANT

CI 18965, known as Tartrazine or FD&C Yellow No. 5, is a synthetic yellow monoazo dye primarily used as a cosmetic colorant. It also temporarily enhances skin transparency, aiding in the visualization of underlying skin structures.

Summary

Colorant Opacity decreasing

Science

Mechanism of Action

As a colorant, it imparts a yellow hue to products. For skin visualization, it alters tissue refractive indices to reduce light scattering, temporarily increasing skin transparency, and absorbs specific wavelengths, particularly red light.

Research

Clinical Evidence

Medium confidence
Effective range 8.27–66.16%
Optimal

N/A

Key findings

  1. 01 Topical application in concentrations from 8.27% to 66.16% (w/v) has shown to improve skin structure visualization and transparency.
  2. 02 Potential utility in evaluating skin barrier dysfunction in atopic dermatitis patients by affecting skin transparency index.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Azo dyes like CI 18965 are prone to photocatalytic degradation, which can lead to the formation of impurities, including potentially harmful aromatic amines.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Regulated in the EU and U.S. for cosmetic use, CI 18965 is a potential allergen and irritant. In vitro studies report genotoxic effects at concentrations as low as 0.116 μg/mL with prolonged exposure, a critical concern for skin health.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

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