Science
Mechanism of Action
Chrysanthemum Indicum Flower Oil functions by neutralizing free radicals, thereby mitigating oxidative stress and supporting healthy aging processes. Its anti-inflammatory compounds help to calm skin sensitivity, reduce redness, and alleviate irritation. The oil also demonstrates antibacterial and antimicrobial efficacy, which can be beneficial in addressing blemish-prone skin and managing microbial imbalances. Additionally, it aids in fortifying the skin's natural barrier, providing conditioning benefits to maintain skin softness, smoothness, and overall resilience.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated significant antioxidant activity in in vitro assays: DPPH (IC50: 2.21 mg/mL), HRS (IC50: 1.90 mg/mL), and SORS (IC50: 4.40 mg/mL).
- 02 Exhibited in vitro antimicrobial activity against Streptococcus agalactiae (MIC: 62.5 µg/mL).
- 03 Showed in vitro antiviral activity against Vesicular Stomatitis Virus (VSV) (IC50: 3.14 µg/mL).
- 04 Demonstrated in vitro anti-mycobacterial activity against M. tuberculosis (IC50: 6.73 µg/mL) and anti-Helicobacter pylori activity (IC50: 3.63 µg/mL).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While direct stability data for Chrysanthemum Indicum Flower Oil is not extensively detailed, studies on related Dendranthema indicum extracts indicate that most components remain stable down to pH 3.4. However, specific components like linalool and citronellal within such extracts demonstrated instability below pH 6.5, suggesting a potential preference for formulations at or above this pH to maintain component integrity.
Safety
Safety Profile
Acute oral toxicity studies in mice showed no mortality or clinical signs of toxicity at 2,000 mg/kg body weight/day, and mutagenicity tests (15.63-500 µg/mL) were negative. However, comprehensive toxicological information specifically for C. indicum flower oil is deemed insufficient to assure its safe use in certain applications. As an essential oil, general recommendations include patch testing prior to widespread use to mitigate risks of skin irritation, allergic reactions, contact dermatitis, or photosensitivity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Chrysanthemum Indicum Flower Oil presents promising in vitro antioxidant, anti-inflammatory, and antimicrobial properties, making it an optional ingredient for formulations targeting comprehensive skin health, though further human clinical data is recommended for definitive efficacy in topical applications.
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