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Moumoujus

CHONDRIA CRASSICAULIS EXTRACT.

Insufficient Data / ANTIMICROBIAL, ANTIOXIDANT

Chondria Crassicaulis Extract, derived from red algae, is a marine ingredient recognized for its potent anti-inflammatory and antioxidant properties. It further contributes to skin revitalization and hydration, addressing multiple concerns for diverse skin types.

Summary

Anti-inflammatory Antioxidant Humectant Moisturizing Antimicrobial Revitalizing Cell Renewal

Science

Mechanism of Action

This extract functions primarily as an anti-inflammatory agent by modulating type 1 and type 2 T helper cells. It demonstrably reduces pro-inflammatory mediators such as beta-hexosaminidase secretion and total immunoglobulin E, concurrently decreasing interleukins (IL-4, IL-5) while elevating anti-inflammatory interferon gamma. Its mechanism extends to inhibiting inflammatory pathways, including cyclooxygenase-2, inducible nitric oxide synthase, NF-κB, and Mitogen-Activated Protein Kinase (MAPK) signaling in macrophages. Furthermore, it exhibits antioxidant capabilities, antimicrobial properties, and contributes to skin remineralization, cell renewal, and humectant (moisturizing) effects.

Research

Clinical Evidence

Low confidence
Effective range 0.1–100%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Data regarding 'dusting' or common over-formulation for Chondria Crassicaulis Extract is not available within the current research.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

A specific optimal pH range for the stability of Chondria Crassicaulis Extract has not been precisely identified. Given its typical extraction methods utilizing solvents like ethanol, the extract is likely soluble and stable in alcohol-water mixtures, containing compounds with both water and organic solubilities. The stability profile may vary depending on the specific formulation and other ingredients.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has determined that there is 'insufficient data' to establish the safety of Chondria Crassicaulis Extract for cosmetic use, as it was not among the 16 red algae-derived ingredients specifically deemed safe out of 60 assessed. While general assessments of various red algae extracts have shown no mortality or severe toxic effects in rats at oral doses up to 2000 mg/kg, specific topical safety data for this extract by CIR, SCCS, or FDA remains undefined.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Chondria Crassicaulis Extract presents promising anti-inflammatory, antioxidant, and moisturizing benefits in preliminary studies, but its comprehensive safety for topical cosmetic applications requires further data based on the CIR Expert Panel's assessment.

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